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Fuel and hormone regulation of phospholipase C β1 and δ1 overexpressed in RINm5F pancreatic beta cells

✍ Scribed by Grant G Kelley; Joanne M Ondrako; Sarah E Reks

Book ID: 117462721
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 464 KB
Volume: 177
Category: Article
ISSN: 0303-7207
DOI: 10.1016/s0303-7207(01)00453-1

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## Abstract In osteoblasts parathyroid hormone (PTH) stimulates the PTH/PTH‐related peptide (PTHrP) receptor (PTH1R) that couples via G~s~ to adenylyl cyclase stimulation and via G~11~ to phospholipase C (PLC) stimulation. We have investigated the effect of increasing G~11~α levels in UMR 106‐01 os