## Abstract ## Background Nonβviral vectorβmediated targeted gene repair could become a useful alternative to classical gene addition strategies. The methodology guarantees a physiologically regulated and persistent expression of the repaired gene, with reported gene conversion and phenotypic corr
Fucosylation in cystic fibrosis airway epithelial cells
β Scribed by Jovin O. Lazatin; Mary Catherine Glick; Thomas F. Scanlin
- Publisher
- Springer US
- Year
- 1994
- Tongue
- English
- Weight
- 692 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1573-4986
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Recombinant human deoxyribonuclease (rhDNase) has been shown to reduce sputum viscoelasticity and to improve lung function in patients with cystic fibrosis (CF). The aim of this study was to determine whether airway inflammation would decrease after administration of rhDNase. Twenty patients with CF
Hyperosmolar aerosols are used to assess airway responsiveness in subjects with asthma. Using a 10% NaCl aerosol, we investigated airway responsiveness in 23 cystic fibrosis (CF) subjects (12 females, 11 males; 19.1 t 3.3 years) who had asthma-like symptoms. The pre-challenge predicted forced expira