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FT-Raman and NIR-SERS characterization of the antimalarial drugs chloroquine and mefloquine and their interaction with hematin

✍ Scribed by S. Cîntǎ-Pînzaru; N. Peica; B. Küstner; S. Schlücker; M. Schmitt; T. Frosch; J. H. Faber; G. Bringmann; J. Popp

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
288 KB
Volume
37
Category
Article
ISSN
0377-0486

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In vitro polarization-resolved resonance
In vitro polarization-resolved resonance Raman studies of the interaction of hematin with the antimalarial drug chloroquine
✍ T. Frosch; B. Küstner; S. Schlücker; A. Szeghalmi; M. Schmitt; W. Kiefer; J. Pop 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 111 KB

## Abstract Despite the public health impact of human malaria, the mechanism of hemozoin inhibition by antimalarial drugs such as chloroquine (CQ) is not yet fully understood. Polarization‐resolved resonance Raman spectra of hematin and its complex with CQ were recorded under Q‐band resonance condi