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Frozen conformers of clotrimazole: Reaction of imidazole with 1-chloro-9-hydroxy-9-phenylxanthene

โœ Scribed by Paul L. Warner Jr.; Edward Luber Jr.; F. Christopher Zusi


Book ID
102405341
Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
244 KB
Volume
68
Category
Article
ISSN
0022-3549

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โœฆ Synopsis


1-Chloro-9-hydroxy-9-phenylxanthene reacts with imidazole at 180 degrees to form a 5:1 mixture of the 9-(imidazo-1-yl)- and 9-(imidazo-2-yl)-1-chloro-9-phenylxanthenes. These products lack significant antifungal activity.


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