Frontline: Peripheral priming of alloreactive T cells by the direct pathway of allorecognition
β Scribed by Myriam Baratin; Karina Bonin; Claude Daniel
- Book ID
- 102167629
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 244 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
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## Cell-type-specific recognition of allogeneic cells by alloreactive cytotoxic T cells: a consequence of peptide-dependent allorecognition* Recently, we provided the first direct evidence that the determinant recognized by some alloreactive cytotoxicT lymphocytes (CTL) clones included an endogeno
w e investigated whether exposure of naive and in vitro pre-activated T cells to CD4 monoclonal antibodies (mAb) could induce specific hyporesponsiveness to a subsequent challenge in the absence of CD4 mAb. Unfractionated peripheral blood mononuclear cells were cultured with mitomycin-treated B cell