A Generic Particle-Based Nonradioactive
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Christine Martens; Alice Bakker; Ana Rodriguez; Richard Bruce Mortensen; Ronald
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Article
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1999
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Elsevier Science
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English
โ 443 KB
We have developed a novel fluorescence-based homogeneous binding assay for high-throughput screening of chemical compounds. In this assay, a Cy5- or Cy5.5-labeled ligand binds to receptor immobilized on a particle, either a bead or a cell. The resulting localized signal can be detected by a modified