(β)-Frontalin: Synthesis using the Catal
(β)-Frontalin: Synthesis using the Catalytic Enantioselective Addition of Dimethylzinc to a Ketone
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Miguel Yus; DiegoΒ J. RamΓ³n; Oscar Prieto
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Article
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2003
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John Wiley and Sons
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English
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## Abstract The first enantioselective synthesis of (β)βfrontalin involving an enantioselective nucleophilic 1,2βaddition of dimethylzinc to a functionalized Ξ±,Ξ²βunsaturated ketone, in the presence of titanium tetraisopropoxide and a substoichiometric amount of the chiral ligand 1,2β__trans__βbis(h