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Frontal lobe atrophy due to a mutation in the cholesterol binding protein HE1/NPC2

✍ Scribed by Hans H. Klünemann; Milan Elleder; Wolfgang E. Kaminski; Karen Snow; Janis M. Peyser; John F. O'Brien; David Munoz; Gerd Schmitz; Helmfried E. Klein; William W. Pendlebury


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
551 KB
Volume
52
Category
Article
ISSN
0364-5134

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A frequent mutation in the acidic prolin
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The human salivary proline-rich proteins (PRPs) are coded by six closely linked genes on chromosome 12p13.2. Two of the PRP genes, PRH1 and PRH2, code for acidic PRPs that are functionally important in binding to teeth surfaces, in maintaining a supersaturated concentration of salivary calcium, and