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From target identification to drug screening assays for neurodegenerative diseases

✍ Scribed by Chiara Zuccato; Marzia Tartari; Donato Goffredo; Elena Cattaneo; Dorotea Rigamonti


Book ID
119346214
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
169 KB
Volume
52
Category
Article
ISSN
1043-6618

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Identification of anti-inflammatory targ
✍ Peter H. Reinhart; Linda S. Kaltenbach; Christian Essrich; Denise E. Dunn; Joshu πŸ“‚ Article πŸ“… 2011 πŸ› Elsevier Science 🌐 English βš– 850 KB

Huntington's disease (HD) is a late-onset, neurodegenerative disease for which there are currently no cures nor disease-modifying treatments. Here we report the identification of several potential anti-inflammatory targets for HD using an ex vivo model of HD that involves the acute transfection of h