✦ LIBER ✦
From sextant to GPS: Twenty-five years of mapping the genome with ChIP
✍ Scribed by David A. Wacker; Tae Hoon Kim
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 148 KB
- Volume
- 107
- Category
- Article
- ISSN
- 0730-2312
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Since its inception, ChIP technology has evolved immensely. Technological advances have improved its specificity and sensitivity, its scale has expanded to a genome‐wide level, and its relative ease of use has made it a virtually ubiquitous tool. This year marks the 25th anniversary of the development of ChIP. In honor of this milestone, we briefly revisit its history, offer a review of recent articles employing ChIP on a genome‐wide scale, and lay out our views for the future of ChIP. J. Cell. Biochem. 107: 6–10, 2009. © 2009 Wiley‐Liss, Inc.