From molecules to networks : an introduction to cellular and molecular neuroscience

✍ Scribed by John H Byrne; Ruth Heidelberger; Melvin Neal Waxham

• Publisher: Elsvier/Academic Press, , Elsevier Inc
• Year: 2014
• Tongue: English
• Leaves: 663
• Edition: 3
• Category: Library

✦ Synopsis

An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. The third edition of From Molecules to Networks provides the solid foundation of the morphological, biochemical, and biophysical properties of nerve cells. In keeping with previous editions, the unique content focus on cellular and molecular neurobiology and related computational neuroscience is maintained and enhanced.

All chapters have been thoroughly revised for this third edition to reflect the significant advances of the past five years. The new edition expands on the network aspects of cellular neurobiology by adding new coverage of specific research methods (e.g., patch-clamp electrophysiology, including applications for ion channel function and transmitter release; ligand binding; structural methods such as x-ray crystallography).

Written and edited by leading experts in the field, the third edition completely and comprehensively updates all chapters of this unique textbook and insures that all references to primary research represent the latest results.

* The first treatment of cellular and molecular neuroscience that includes an introduction to mathematical modeling and simulation approaches

* 80% updated and new content

* New Chapter on "Biophysics of Voltage-Gated Ion Channels"

* New Chapter on "Synaptic Plasticity"

* Includes a chapter on the Neurobiology of Disease

* Highly referenced, comprehensive and quantitative

* Full color, professional graphics throughout

* All graphics are available in electronic version for teaching purposes

✦ Table of Contents

Content:
Front-matter, Pages i,iii
Copyright, Page iv
Preface to the Third Edition, Page ix, John H. Byrne, Ruth Heidelberger, M. Neal Waxham
Preface to the Second Edition, Page xi, John H. Byrne, James L. Roberts
Preface to the First Edition, Page xiii, John H. Byrne, James L. Roberts
List of Contributors, Pages xv-xvi, Cristina M. Alberini, Douglas A. Baxter, Andrew J. Bean, Michael Beierlein, Scott Brady, Peter Brophy, John H. Byrne, David R. Colman, Javier DeFelipe, Ariel Y. Deutch, Gerald A. Dienel, Gregory A. Elder, Monica Gireud, Andrea Giuffrida, Ruth Heidelberger, Lily Yeh Jan, Yuh Nung Jan, Patrick R. Hof, Pascal S. Kaeser, Grahame Kidd, Eric Klann, et al.
Chapter 1 - Cellular Components of Nervous Tissue, Pages 3-21, Patrick R. Hof, Grahame Kidd, Javier DeFelipe, Jean de Vellis, Miguel A. Gama Sosa, Gregory A. Elder, Bruce D. Trapp
Chapter 2 - Subcellular Organization of the Nervous System: Organelles and Their Functions, Pages 23-52, Scott Brady, David R. Colman, Peter Brophy
Chapter 3 - Energy Metabolism in the Brain, Pages 53-117, Gerald A. Dienel
Chapter 4 - Intracellular Signaling, Pages 119-148, Howard Schulman
Chapter 5 - Regulation of Neuronal Gene Expression and Protein Synthesis, Pages 149-174, Cristina M. Alberini, Eric Klann
Chapter 6 - Modeling and Analysis of Intracellular Signaling Pathways, Pages 175-205, Paul D. Smolen, Douglas A. Baxter, John H. Byrne
Chapter 7 - Pharmacology and Biochemistry of Synaptic Transmission: Classical Transmitters, Pages 207-237, Ariel Y. Deutch, Robert H. Roth
Chapter 8 - Nonclassic Signaling in the Brain, Pages 239-255, Ariel Y. Deutch, Andrea Giuffrida, James L. Roberts
Chapter 9 - Connexin and Pannexin Based Channels in the Nervous System: Gap Junctions and More, Pages 257-283, Juan C. Sáez, Bruce Nicholson
Chapter 10 - Neurotransmitter Receptors, Pages 285-321, M. Neal Waxham
Chapter 11 - Molecular Properties of Ion Channels, Pages 323-348, Jason Tien, David Matthew Young, Yuh Nung Jan, Lily Yeh Jan
Chapter 12 - Membrane Potential and Action Potential, Pages 351-376, David A. McCormick
Chapter 13 - Biophysics of Voltage-Gated Ion Channels, Pages 377-407, Diane Lipscombe, Cecilia P. Toro
Chapter 14 - Dynamical Properties of Excitable Membranes, Pages 409-442, Douglas A. Baxter, John H. Byrne
Chapter 15 - Release of Neurotransmitters, Pages 443-488, Robert S. Zucker, Dimitri M. Kullmann, Pascal S. Kaeser
Chapter 16 - Postsynaptic Potentials and Synaptic Integration, Pages 489-507, John H. Byrne
Chapter 17 - Cable Properties and Information Processing in Dendrites, Pages 509-529, Michael Beierlein
Chapter 18 - Synaptic Plasticity, Pages 533-561, Ruth Heidelberger, Harel Shouval, Robert S. Zucker, John H. Byrne
Chapter 19 - Information Processing in Neural Networks, Pages 563-589, James J. Knierim
Chapter 20 - Learning and Memory: Basic Mechanisms, Pages 591-637, John H. Byrne, Kevin S. LaBar, Joseph E. LeDoux, Glenn E. Schafe, Richard F. Thompson
Chapter 21 - Molecular Mechanisms of Neurological Disease, Pages 639-661, Monica Gireud, Natalie Sirisaengtaksin, Andrew J. Bean
Index, Pages 663-675