From Metal Binding to Nanoparticle Formation: Monitoring Biomimetic Iron Oxide Synthesis within Protein Cages using Mass Spectrometry

✍ Scribed by Sebyung Kang; Craig C. Jolley; Lars O. Liepold; Mark Young; Trevor Douglas

• Book ID: 102728239
• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 711 KB
• Volume: 48
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.200900437

✦ Synopsis

Abstract

Mass measurements of metal‐mineralized protein cages allowed quantitative examination of the effects of metal‐ion concentration on the final nanoparticle size. Modeling using a kinetic master equation suggests that particle growth involves both a binding phase and a growth phase (see picture; I: relative abundance; LiDps: a DNA binding protein; ^n^Fe: number of Fe atoms).magnified image