From intermolecular alcohol additions on a double bond to electrocyclizations of non-activated γ, δ-unsaturated alcohols: An easy synthesis of tetrahydrofurans

✍ Scribed by Xavier Franck; Bruno Figadére; André Cavé

• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 135 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)00081-6

✦ Synopsis

Tetrahydrofurans have been synthesized in high yields through an electrocyclization reaction, by simple treatment of non activated y, 8-or 1~, y--unsaturated alcohols with an acidic resin (Amberlyst H-15) in CH2C12 at room temperature.