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✦   LIBER   ✦

From global expression data to gene networks

✍ Scribed by Denis Thieffry

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
100 KB
Volume
21
Category
Article
ISSN
0265-9247

No coin nor oath required. For personal study only.

✦ Synopsis

Allowing the parallel monitoring of the transcription of thousands of genes, microarrays constitute a powerful technique for functional genomics. In a recent paper, a clustering method and a local alignment software were combined to identify DNA motifs in sets of yeast genes endowed with similar transcription profiles throughout mitosis (1) . Identifying various known transcriptional binding sites together with new putative ones, the authors made a significant step towards a systematic characterization of the regulatory structure of genomic networks.

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