𝔖 Bobbio Scriptorium
✦   LIBER   ✦

From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases

✍ Scribed by Vinod Kumar, Cisca Wijmenga, Sebo Withoff

Book ID
118781476
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
878 KB
Volume
34
Category
Article
ISSN
1863-2297

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Estimating Missing Heritability for Dise
Estimating Missing Heritability for Disease from Genome-wide Association Studies
✍ Sang Hong Lee; Naomi R. Wray; Michael E. Goddard; Peter M. Visscher 📂 Article 📅 2011 🏛 American Society of Human Genetics 🌐 English ⚖ 183 KB

Genome-wide association studies are designed to discover SNPs that are associated with a complex trait. Employing strict significance thresholds when testing individual SNPs avoids false positives at the expense of increasing false negatives. Recently, we developed a method for quantitative traits t