✦ LIBER ✦

From expressed sequence tags to ‘epigenomics’: an understanding of disease processes

✍ Scribed by Gary Zweiger; Randal W Scott

Book ID: 104362052
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 432 KB
Volume: 8
Category: Article
ISSN: 0958-1669
DOI: 10.1016/s0958-1669(97)80119-x

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✦ Synopsis

Expressed sequence tags (ESTs) are at the forefront of technological change that is sweeping the biomedical research community. ESTs provide a high throughput means for identifying gene transcripts and monitoring complex gene expression patterns. EST-based technologies coupled with sophisticated computer analysis tools enable the informational content and output of the genome to be accessed and evaluated on a scale immensely larger than previously possible. EST-based technologies are being used to understand disease processes and to find better disease treatments, and will allow biology to move from single gene to multigene, or even more complex epigenetic, explanations for disease.

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