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From crucial to negligible: Functional CD8+T-cell responses and their dependence on CD4+T-cell help

✍ Scribed by Melanie Wiesel; Annette Oxenius

Book ID
112082208
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
604 KB
Volume
42
Category
Article
ISSN
0014-2980

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πŸ“œ SIMILAR VOLUMES

CD4 T cell help is required for primary
CD4 T cell help is required for primary CD8 T cell responses to vesicular antigen delivered to dendritic cells in vivo
✍ Karine Serre; Laurent Giraudo; Carole Siret; Lee Leserman; Patrick Machy πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 553 KB

## Abstract Insight into the mechanisms by which dendritic cells (DC) present exogenous antigen to T cells is of major importance in the design of vaccines. We examined the effectiveness of free antigen as well as antigen with lipopolysaccharide, emulsified in complete Freund's adjuvant, and antige