Modern Arene Chemistry || From Acetylene
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Astruc, Didier
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Article
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2002
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Wiley-VCH Verlag GmbH & Co. KGaA
β 526 KB
Alkynes have been used as precursors for aromatic compounds since Berthelot converted acetylene to benzene in 1867. The review presents new evidence on the mechanism of this first total synthesis of an aromatic compound. Presumably, its last step involves the thermocyclization of hexa-1,3-dien-5-yne