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From AACR—Genetics: Alterations revealed in head and neck cancer


Book ID
120244507
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
45 KB
Volume
10
Category
Article
ISSN
1759-4774

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TP53 genetic alterations in head-and-nec
✍ Maria A. Nagai; Elisabete C. Miracca; Lidia Yamamoto; Ricardo P. Moura; Andrew J 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 170 KB 👁 2 views

In this study we investigated the incidence of mutations and loss of heterozygosity (LOH) of the TP53 gene in DNA samples from paired tumor and adjacent normal tissue from 90 patients with untreated squamous-cell carcinoma of the head and neck. Evidence for TP53 mutations were demonstrated in 53% (4