Friend leukaemia virus-transformed cells, unlike normal stem cells, form spleen colonies in Sl/Sld mice

Organ interactions in the regulation of

Organ interactions in the regulation of hematopoiesis: In vitro interactions of bone, thymus, and spleen with bone marrow stem cells in normal, Sl/Sld and W/Wv mice

✍ Martin J. Cline; Carol Le Fevre; David W. Golde 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 781 KB

## Abstract Hematopoietic cell differentiation is influenced by organ‐dependent microenvironmental factors as well as humoral regulators. A technique is described for examining certain aspects of the hemopoietic inductive microenvironment in vitro. Suspension and agar cultures of mouse bone marrow