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Friedel–Crafts Benzylation of Activated and Deactivated Arenes

✍ Scribed by Gabriel Schäfer; Prof. Dr. Jeffrey W. Bode


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
340 KB
Volume
50
Category
Article
ISSN
0044-8249

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## Abstract “__Deficient” but “efficient__”, the first example of a catalytic Friedel–Crafts alkylation of arenes, carrying electron‐withdrawing groups, with alcohols is reported. The optimized iron(III) chloride (97%) catalyzed allylation, benzylation and propargylation procedures open an access t