Frequent β-catenin overexpression without exon 3 mutation in cutaneous lymphomas
✍ Scribed by Bellei, Barbara; Pacchiarotti, Alberto; Perez, Marie; Faraggiana, Tullio
- Book ID
- 109888027
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 276 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0893-3952
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Beta-catenin plays an important role in the Wnt signaling pathway by activating T-cell factor (Tcf)/lymphoid enhancer factor (Lef)-regulated gene transcription. The level of beta-catenin is regulated through GSK-3beta phosphorylation of specific serine and threonine residues, all of which are encode
The molecular mechanisms involved in the generation of epithelial ovarian cancers are poorly understood, but evidence suggests that the different histological subtypes may arise from independent tumorigenic events. -Catenin is emerging as an important oncogene in the transformation of a number of e