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Frequent spontaneous sister chromatid exchange in hepatocytes of transgenic mice harboring the SV40-T antigen gene

โœ Scribed by Jia Liu; Hong Li; Kimie Nomura; Keiko Ohtake; Tomoyuki Kitagawa


Book ID
112498178
Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
986 KB
Volume
118
Category
Article
ISSN
1432-1335

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## Abstract Previous studies in this laboratory have demonstrated that the earliest cytogenetic alteration in the development of hepatic neoplasms in a transgenic strain of rats bearing the albumin Simian virus 40 T antigen (Alb SV40 T Ag) construct was a duplication of the chromosome 1q4.1โ€1q4.2 b