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Frequent mutation in North African patients with MUTYH-associated polyposis

✍ Scribed by JH Lefevre; C Colas; F Coulet; S Baert-Desurmont; C Mongin; E Tiret; T Frebourg; F Soubrier; Y Parc


Book ID
110889132
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
543 KB
Volume
80
Category
Article
ISSN
0009-9163

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## Abstract To determine the frequency, mutation spectrum and phenotype of the recently described autosomal recessive __MUTYH__‐associated polyposis (MAP), we performed a systematic search for __MUTYH (MYH__) mutations by sequencing the complete coding region of the gene in 329 unselected __APC__ m