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Frequent loss of heterozygosity in the region of D1S450 at 1p36.2 in myelodysplastic syndromes

✍ Scribed by Wolf-K Hofmann; Seisho Takeuchi; Dong Xie; Carl W Miller; Dieter Hoelzer; H.Phillip Koeffler


Book ID
114119001
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
129 KB
Volume
25
Category
Article
ISSN
0145-2126

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Loss of heterozygosity (LOH) of the long arm of chromosome 7 occurs frequently in many types of primary cancers. We analyzed 22 primary ovarian cancers for LOH of chromosome arm 7q using a set of 16 microsatellite markers in order to determine the location of a putative tumor suppressor gene (TSG).