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Frequent epigenetic inactivation of the SLIT2 gene in gliomas

✍ Scribed by Dallol, Ashraf; Krex, Dietmar; Hesson, Luke; Eng, Charis; Maher, Eamonn R; Latif, Farida

Book ID
110067780
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
285 KB
Volume
22
Category
Article
ISSN
0950-9232

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## Abstract ## Background Epigenetic silencing of tumor suppressor genes plays an important role in nasopharyngeal carcinoma (NPC) tumorigenesis. In the present study, we explore a novel target gene of epigenetic silencing in NPC, __Myocardin__, which is inactivated by promoter hypermethylation.