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Frequent epigenetic inactivation of RSK4 by promoter methylation in cancerous and non-cancerous tissues of breast cancer

✍ Scribed by Li, Qiuyun; Jiang, Yi; Wei, Wei; Ji, Yinan; Gao, Hui; Liu, Jianlun

Book ID: 121577987
Publisher: Springer US
Year: 2013
Tongue: English
Weight: 558 KB
Volume: 31
Category: Article
ISSN: 1357-0560
DOI: 10.1007/s12032-013-0793-3

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## Abstract Epigenetic modification of gene expression plays an important role in the development of human cancers. The inactivation of __SPARC__ through CpG island methylation was studied in colon cancers using oligonucleotide microarray analysis and methylation specific PCR (MSP). Gene expression