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Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias

✍ Scribed by Lawrence, HJ; Rozenfeld, S; Cruz, C; Matsukuma, K; Kwong, A; Kömüves, L; Buchberg, AM; Largman, C


Book ID
110054362
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
175 KB
Volume
13
Category
Article
ISSN
0887-6924

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Translocation (7;11)(p15;p15) is uncommon in acute myeloid leukemia (AML) and may have a predilection to occur in Asian patients. It results in a reciprocal fusion of the homeobox gene HOXA9 and the nucleoporin gene NUP98. To ascertain the molecular features and the clinicopathological and prognosti