Small cell lung cancer (SCLC) cell lines and tumors invariably exhibit loss of heterozygosity (LOH) or, in rare cases, homozygous deletions involving part or all of chromosome arm 3p, suggesting the presence of 1 or more tumor-suppressor genes in this region. The gene encoding aminoacylase-1 (ACY1)
Frequent BRG1/SMARCA4–inactivating mutations in human lung cancer cell lines
✍ Scribed by Pedro P. Medina; Octavio A. Romero; Takashi Kohno; Luis M. Montuenga; Ruben Pio; Jun Yokota; Montse Sanchez-Cespedes
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 289 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1059-7794
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