The base-alteration spectrum of spontane
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Lee, Grace S. -F. ;Savage, Elizabeth A. ;Ritzel, R. Gary ;von Borstel, R. C.
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Article
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1988
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Springer
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English
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A forward mutation system has been developed to obtain rapidly clonable mutants at the URA3 locus in yeast by means of selection for 5-fluoroorotic acid resistance. We have used this system to determine base changes in 35 spontaneous and 34 ultraviolet radiation-induced ura3 base substitution mutant