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Frequency of HPRT mutant lymphocytes in a human control population as determined by the T-cell cloning procedure

✍ Scribed by Edith Hüttner; Bettina Holzapfel; Siegfried Kropf


Book ID
113255937
Publisher
Elsevier Science
Year
1995
Weight
597 KB
Volume
348
Category
Article
ISSN
0165-7992

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nine resistant T-lymphocytes were isolated from two blood samples obtained 4 months apart from a 50year-old male subiect. Sixty-six of these mutants were characterized at the DNA sequence level using cDNA. One particular single base substitution was recovered a total of 23 fimes. The majority of T-c