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Frequency of congenital defects and dominant lethals in the offspring of male mice treated with methylnitrosourea

✍ Scribed by N. Nagao


Book ID
113193101
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
541 KB
Volume
177
Category
Article
ISSN
0027-5107

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Male mice of inbred strain A/J were intraperitoneally treated with ethylnitrosourea (ENU). On day 64-82 posttreatment, the males were mated with untreated virgin females of the same strain. Copulation involved sperm that were spermatogonial stem cells at the time of treatment. On day 18 of gestation