Frequency and treatment of depressive symptoms in a Parkinson's disease registry
✍ Scribed by Astrid Althaus; Oliver Arránz Becker; Annika Spottke; Reinhard Dengler; Frank Schneider; Manja Kloss; Karla Eggert; Wolfgang H. Oertel; Ulrich Dillmann; Birgit Herting; Joseph Classen; Richard Dodel
- Book ID
- 116820470
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 177 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1353-8020
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## Abstract ## Objective Depression is a common neuropsychiatric syndrome in Parkinson's disease (PD), and may be etiologically related to the neurochemical changes accompanying this disease. It is still unclear whether the disturbances of neurotransmitter activities lead to a specific profile of
## Abstract Little is known about the course of depressive symptoms in Parkinson's disease (PD). We studied the course of clinically significant depressive symptoms using data from two clinical trials that followed 413 early, untreated PD subjects for 12 to 18 months. We measured depressive symptom