Antibodies to actin have been proposed as diagnostic markers for type 1 autoimmune hepatitis. Our aims were to determine 1) if testing for antibodies to actin is superior to testing for smooth muscle antibodies (SMA); 2) if these antibodies identify patients with distinctive clinical features; and 3
Frequency and significance of antibodies to asialoglycoprotein receptor in type 1 autoimmune hepatitis
โ Scribed by Albert J. Czaja; Karin D. Pfeifer; Richard H. Decker; Ana S. Vallari
- Publisher
- Springer US
- Year
- 1996
- Tongue
- English
- Weight
- 1003 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0163-2116
No coin nor oath required. For personal study only.
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Autoantibodies to the human asialoglycoprotein receptor (anti-h-ASGPR) were studied with a solid-phase ELISA in the sera of 421 patients with inflammatory liver diseases, 288 patients with various other disorders and 31 controls. Anti-h-ASGPR were found predominantly in autoimmune chronic active hep
Perinuclear anti-neutrophil cytoplasmic antibodies (pANCA) have been recently defined as the most sensitive autoantibody of type 1 autoimmune hepatitis (AIH-1). Their prevalence in type 2 autoimmune hepatitis (AIH-2) has not yet been evaluated. The aim of the present study was to verify the associat
Genetic involvement in type 1 autoimmune hepatitis (AIH) is indicated by a marked female preponderance and strong, well-established, human leukocyte antigen (HLA) associations. These associations, however, are not universal and a number of genes outside the major histocompatibility complex may also
dsDNA were shown in 64% of patients with autoimmune To determine the significance of antibodies to singlehepatitis, 46% with cryptogenic hepatitis, and 43% with stranded (anti-ssDNA) and double-stranded DNA (antichronic hepatitis B. 8 Tsuchiya and colleagues, using an ELISA dsDNA) in antinuclear ant