Frequencies of estrogen receptor mRNAs splice variants in various human mammary tissues
β Scribed by Masao Hori; Motonobu Katano; Yuji Asato; Masayuki Itabashi
- Publisher
- Springer Japan
- Year
- 1998
- Tongue
- English
- Weight
- 902 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1340-6868
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We have carried out a quantitative analysis of ER-alpha and ER-beta mRNA expression in normal (n = 11) and breast cancer (n = 112) tissues using a real-time (Taq-Man) PCR assay. Expression of ER-beta mRNA variants has also been studied by triple-primer PCR assay. ER-alpha mRNA levels in normal breas
Androgens and androgen receptor (AR) are involved in many regulatory processes in the growth of female breast cells. Mutations in the AR gene and/or alterations of the AR protein sequence may be related to the development and progression of breast cancer. Using reverse transcriptionpolymerase chain