## Abstract CD4^+^CD25^hi^CTLA4^+^FoxP3^+^ regulatory T cells (Treg) have been shown to maintain immune tolerance against self antigens and increased circulating frequencies have been reported in various types of cancers. Circulating invariant natural killer Tβcells (iNKT) are reduced in cancer pat
Frequencies and role of regulatory T cells in patients with (pre)malignant cervical neoplasia
β Scribed by J. Visser; H. W. Nijman; B.-N. Hoogenboom; P. Jager; D. Van Baarle; E. Schuuring; W. Abdulahad; F. Miedema; A. G. Van Der Zee; T. Daemen
- Book ID
- 108699678
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 313 KB
- Volume
- 150
- Category
- Article
- ISSN
- 0009-9104
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## Abstract ## BACKGROUND Active suppression by CD4^+^CD25^+^ regulatory T cells plays an important role in the downβregulation of the response of T cells to foreign and self antigens. Experimental tumor models in mice revealed that regulatory T cells inhibit antitumor immune responses. The purpos