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Freezing of gait in patients with advanced Parkinson's disease

✍ Scribed by N. Giladi; T. A. Treves; E. S. Simon; H. Shabtai; Y. Orlov; B. Kandinov; D. Paleacu; A. D. Korczyn


Publisher
Springer
Year
2001
Tongue
English
Weight
79 KB
Volume
108
Category
Article
ISSN
1435-1463

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## Abstract Freezing of gait (FOG) is a frequent, disabling symptom of Parkinson's disease (PD). FOG usually lasts a few seconds. It refers to brief paroxysmal events during which a subject is unable to start or continue locomotion. Despite its frequency, FOG pathophysiology is unclear. Because a f

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## Abstract To revalidate the Freezing of Gait Questionnaire (FOG‐Q), patients with Parkinson's disease (PD) were randomly assigned to receive rasagiline (1 mg/day) (n = 150), entacapone (200 mg with each dose of levodopa) (n = 150), or placebo (n = 154). Patients were assessed at baseline and afte

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## Abstract Freezing of gait (FOG) is one of the most disabling symptoms that affect patients with Parkinson's disease (PD). Although the pathophysiology underlying FOG largely remains an enigma, several lines of evidence suggest that the autonomic nervous system might be involved. To this end, we

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## Abstract Freezing of gait in Parkinson's disease can be difficult to study in the laboratory. Here we investigate the use of a variable‐width doorway to provoke freeze behavior together with new objective methods to measure it. With this approach we compare the effects of anti‐parkinsonian treat

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Freezing of gait (FOG) has been known to respond favorably to sensory tricks and cues. However, FOG is a complex phenomenon with various motor control deficits at play. In this review, we examined and summarized the currently available evidence for the effectiveness of cueing for FOG to determine it