Free volume study on calcification process in an intraocular lens after cataract surgery
✍ Scribed by R. Ramani; J.K.S. Parihar; C. Ranganathaiah; P. Awasthi; S. Alam; G.N. Mathur
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 162 KB
- Volume
- 75B
- Category
- Article
- ISSN
- 1552-4973
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✦ Synopsis
Abstract
An opacified intraocular lens explanted from a patient in the postoperative period after phacoemulsification was investigated to find the cause of opacification. From the UV‐visible and energy dispersive X‐ray spectroscopy (EDS) measurements, the opacification in the present case seems to be due to calcification of the intraocular lens and not due to modification in the UV absorber material of the lens. The average free volume size of the intraocular lens both in unimplanted and explanted state were obtained from positron lifetime spectroscopy (PLS). Further, the combined FTIR and PLS results indicate that calcium gets into the free volume cavities of the intraocular lens matrix as a cationic moiety, may be in the form of Ca^++^. The small decrease in glass transition temperature of the calcified lens seems to indicate the plasticizing action of calcium ions. The present results could be of some use in the design of the intraocular lens material in which calcification would be minimum. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2005