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Free radicals and lipid peroxidation do not mediate β-amyloid-induced neuronal cell death

✍ Scribed by Zhi-Xing Yao; Katy Drieu; Luke I. Szweda; Vassilios Papadopoulos


Book ID
114005386
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
227 KB
Volume
847
Category
Article
ISSN
0006-8993

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## Abstract Early intracellular events responsible for cell‐cycle induction by β‐amyloid (Aβ) in neurons have not been identified yet. Extracellular signal–regulated kinases 1/2 (ERK1/2) have been identified in this pathway, and inhibition of ERK activity prevents cell‐cycle activation and reduces