Integrins mediate β-amyloid-induced cell
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Giuseppina Frasca; Viviana Carbonaro; Sara Merlo; Agata Copani; Maria Angela Sor
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Article
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2008
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John Wiley and Sons
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English
⚖ 233 KB
## Abstract Early intracellular events responsible for cell‐cycle induction by β‐amyloid (Aβ) in neurons have not been identified yet. Extracellular signal–regulated kinases 1/2 (ERK1/2) have been identified in this pathway, and inhibition of ERK activity prevents cell‐cycle activation and reduces