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Free radical-mediated damage to brain in Alzheimer's disease and its transgenic mouse models

✍ Scribed by Joshua A. Sonnen; John C. Breitner; Mark A. Lovell; William R. Markesbery; Joseph F. Quinn; Thomas J. Montine


Book ID
113630596
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
276 KB
Volume
45
Category
Article
ISSN
0891-5849

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Free radical damage to cerebral cortex i
✍ Joshua A. Sonnen; Eric B. Larson; Shelly L. Gray; Angela Wilson; Steven G. Koham πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 93 KB

## Abstract Evidence supports a pathogenic role for free radical injury to brain in Alzheimer's disease; however, clinical trial results are only mildly encouraging. Examining brains from The Adult Changes in Thought study offers a unique perspective. Selectively increased free radical damage to ce