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Free light chains of immunoglobulins in the cerebrospinal fluid of human immunodeficiency virus type 1-infected patients

✍ Scribed by Paolo Gallo; Maria Grazia Piccinno; Anita De Rossi; Silvana Pagni; Alberto Amadori; Luigi Chieco-Bianchi; Bruno Tavolato


Book ID
119107497
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
659 KB
Volume
26
Category
Article
ISSN
0165-5728

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Progressive multifocal leukoencephalopathy (PML) is a lytic infection of oligodendrocytes by the human papovavirus JC. Patients with defects in cell-mediated immunity are at risk for active disease: a usually lethal demyelination of the brain. PML develops in at least 4% of patients with the acquire