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Free energy landscapes for initiation and branching of protein aggregation

✍ Scribed by Zheng, W.; Schafer, N. P.; Wolynes, P. G.


Book ID
121429093
Publisher
National Academy of Sciences
Year
2013
Tongue
English
Weight
882 KB
Volume
110
Category
Article
ISSN
0027-8424

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## Abstract The properties of the amyloid‐β peptide that lead to aggregation associated with Alzheimer's disease are not fully understood. This study aims at identifying conformational differences among four variants of full‐length AΞ²42 that are known to display very different aggregation propertie