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Free energy calculations on dimer stability of the HIV protease using molecular dynamics and a continuum solvent model

✍ Scribed by Wei Wang; Peter A Kollman

Book ID: 117979578
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 291 KB
Volume: 303
Category: Article
ISSN: 0022-2836
DOI: 10.1006/jmbi.2000.4057

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## Abstract SL1 is a stem–loop RNA sequence from the genome of HIV‐1 thought to be the initiation site for the dimerization of the retroviral genomic RNA. The aim of this study is to check the stability in solution of different experimental dimeric structures available in the literature. Two kinds