𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Free calcium transients and oscillations in nerve cells

✍ Scribed by P. G. Kostyuk; P. V. Belan; A. V. Tepikin

Publisher
Springer-Verlag
Year
1991
Tongue
English
Weight
530 KB
Volume
83
Category
Article
ISSN
0014-4819

No coin nor oath required. For personal study only.

✦ Synopsis

Changes in the intracellular level of free calcium induced by different influences in neurones of the snail Helix pomatia have been measured by changes in Fura-2 fluorescence. Thymol in submillimolar concentrations induced the release of stored intracellular calcium. This effect was similar to xanthine-induced release. IP3 and Gpp[NH]p injections also released intracellular calcium. The response to cAMP injections was more complicated and included, probably, both the release of stored calcium and its influx through membrane channels. Oscillations of intracellular free calcium are described. It has been suggested that oscillations can occur only in cases where the mechanism of Ca-dependent calcium release is activated.

πŸ“œ SIMILAR VOLUMES

Neuroprotective compounds inhibit depola
Neuroprotective compounds inhibit depolarisation-evoked calcium transients in granule cells
✍ Jean-Pierre Hubert; Adam Doble πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 158 KB

The effects of several neuroprotective or anticonvulsant compounds on depolarisation-evoked calcium mobilisation in cultured rat cerebellar granule cells were compared using a calcium imaging method. Calcium transients were evoked by brief stimulations with N-methyl-D-aspartate (NMDA), veratridine,

Calcium oscillations induced by gambiero
Calcium oscillations induced by gambierol in cerebellar granule cells
✍ E. Alonso; C. Vale; M. Sasaki; H. Fuwa; Y. Konno; S. Perez; M.R. Vieytes; L.M. B πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 341 KB

## Abstract Gambierol is a marine polyether ladder toxin derived from the dinoflagellate __Gambierdiscus toxicus__. To date, gambierol has been reported to act either as a partial agonist or as an antagonist of sodium channels or as a blocker of voltage‐dependent potassium channels. In this work, w