Frederick T. Chin, Cheryl L. Morse, H. Umesha Shetty and Victor W. Pike, automated radiosynthesis of [18F]SPA-RQ for imaging human brain NK1 receptors with PET. J Label Compd Radiopharm 2005; 49: 17-31

Automated radiosynthesis of [18F]SPA-RQ

Automated radiosynthesis of [18F]SPA-RQ for imaging human brain NK1 receptors with PET

✍ Frederick T. Chin; Cheryl L. Morse; H. Umesha Shetty; Victor W. Pike 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 316 KB

## Abstract [^18^F]SPA‐RQ is an effective radioligand for imaging brain neurokinin type‐1 (NK~1~) receptors in clinical research and drug discovery with positron emission tomography. For the automated regular production of [^18^F]SPA‐RQ for clinical use in the USA under an IND we chose to use a mod