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FRAT1 expression and its correlation with pathologic grade, proliferation, and apoptosis in human astrocytomas

✍ Scribed by Geng Guo; Bolin Liu; Chengliang Zhong; Xiang Zhang; Xinggang Mao; Peng Wang; Xiaofan Jiang; Junli Huo; Ji Jin; Xiaodong Liu; Xiaoyan Chen

Publisher: Springer US
Year: 2009
Tongue: English
Weight: 411 KB
Volume: 28
Category: Article
ISSN: 1357-0560
DOI: 10.1007/s12032-009-9402-x

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## Abstract ## BACKGROUND An unbalance of cell proliferation and cell apoptosis is an important mechanism in carcinogenesis, and angiogenesis also plays a crucial role in tumorigenesis. Recently, survivin has been identified as an important member of the inhibitor of apoptosis protein (IAP) family