✦ LIBER ✦

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways

✍ Scribed by van Amerongen, R; Nawijn, M C; Lambooij, J -P; Proost, N; Jonkers, J; Berns, A

Book ID: 109971101
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 920 KB
Volume: 29
Category: Article
ISSN: 0950-9232
DOI: 10.1038/onc.2009.310

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Cultured endothelial cells display endog

Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling

✍ Anne M. Goodwin; Kaitlyn M. Sullivan; Patricia A. D'Amore 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 606 KB

PKCζ at the crossroad of NF-κB and Jak1/

PKCζ at the crossroad of NF-κB and Jak1/Stat6 signaling pathways

✍ Moscat, J; Rennert, P; Diaz-Meco, M T 📂 Article 📅 2005 🏛 Nature Publishing Group 🌐 English ⚖ 155 KB

Wnt3a stimulates Mepe, Matrix extracellu

Wnt3a stimulates Mepe, Matrix extracellular phosphoglycoprotein, expression directly by the activation of the canonical Wnt signaling pathway and indirectly through the stimulation of autocrine Bmp-2 expression

✍ Young-Dan Cho; Woo-Jin Kim; Won-Joon Yoon; Kyung-Mi Woo; Jeong-Hwa Baek; Gene Le 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 576 KB

## Abstract __M__atrix __e__xtracellular __p__hosphoglycoprot__e__in (MEPE) is a specific marker of mineralizing osteoblasts and osteocytes. Canonical BMP and Wnt signaling pathways are two of the strongest paracrine signals stimulating osteogenesis. Our previous results indicated that __Mepe__ exp

Colorectal cancers show distinct mutatio

Colorectal cancers show distinct mutation spectra in members of the canonical WNT signaling pathway according to their anatomical location and type of genetic instability

✍ Cristina Albuquerque; Célia Baltazar; Bruno Filipe; Filipa Penha; Teresa Pereira 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 962 KB

## Abstract It is unclear whether the mutation spectra in WNT genes vary among distinct types of colorectal tumors. We have analyzed mutations in specific WNT genes in a cohort of 52 colorectal tumors and performed a meta‐analysis of previous studies. Notably, significant differences were found amo

At the crossroads of differentiation and

At the crossroads of differentiation and proliferation: Precise control of cell-cycle changes by multiple signaling pathways in Drosophila follicle cells

✍ Stephen Klusza; Wu-Min Deng 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 596 KB

## Abstract Here, we discuss the findings to date about genes and pathways required for regulation of somatic follicle‐cell proliferation and differentiation during __Drosophila__ oogenesis and demonstrate how loss of these genes contributes to the tumorigenic potential of mutant cells. Follicle ce

A novel target for Huntington's disease:

A novel target for Huntington's disease: ERK at the crossroads of signaling : The ERK signaling pathway is implicated in Huntington's disease and its upregulation ameliorates pathology

✍ Bodai, László (author);Marsh, J. Lawrence (author) 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 300 KB 👁 1 views

## Abstract Activating the ERK pathway (extracellular signal‐regulated kinase pathway) has proven beneficial in several models of Huntington's disease (HD), and drugs that are protective in HD models have recently been found to activate ERK. Thus, the ERK cascade may be a potential target for thera