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Fragment Informatics and Computational Fragment-Based Drug Design: An Overview and Update

✍ Scribed by Chunquan Sheng; Wannian Zhang


Book ID
112143501
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
1019 KB
Volume
33
Category
Article
ISSN
0198-6325

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Fragment-based quantitative structure–ac
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## Abstract In cooperation with the fragment‐based design a new drug design method, the so‐called “fragment‐based quantitative structure–activity relationship” (FB‐QSAR) is proposed. The essence of the new method is that the molecular framework in a family of drug candidates are divided into severa