Fragment-based drug discovery

Publisher: Royal Soc Of Chemistry
Year: 2014
Tongue: English
Leaves: 313
Category: Library

No coin nor oath required. For personal study only.

✦ Table of Contents

Content: Different flavours of Fragments
Advances in SPR Technology
Applications of NMR in Fragment-Based Drug Discovery
Issues around Fragments as an Approach, including a Computational/in silico Perspectives on Fragment-Based Drug Discovery
Fragment-Based Drug Discovery of Kinase Inhibitors
Fragment-Based Discovery of Antibacterials
Strategies for Fragment-Based Lead Generation
Fragment-Based Approaches to Epigenetic Targets
Application of Fragment-Based Drug Discovery to GPCRs
Fragment-Based Drug Discovery applied to Protein-Protein Interactions
Probing Difficult Targets

📜 SIMILAR VOLUMES

Fragment-Based Drug Discovery

📁 Fragment-Based Drug Discovery

✍ Steven Howard, Chris Abell (eds.) 📂 Library 📅 2015 🏛 Royal Society of Chemistry 🌐 English

<P>Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is

Fragment-Based Drug Discovery

📁 Fragment-Based Drug Discovery

✍ Steven Howard, Chris Abell (eds.) 📂 Library 📅 2015 🏛 Royal Society of Chemistry 🌐 English

Fragment-Based Methods in Drug Discovery

📁 Fragment-Based Methods in Drug Discovery

✍ Anthony E. Klon (eds.) 📂 Library 📅 2015 🏛 Humana Press 🌐 English

<p><p>This volume covers the techniques necessary for a successful fragment-based drug design project, beginning from defining the problem in terms of preparing the protein model, identifying potential binding sites, and the consideration of various candidate fragments for simulation. The second par

Fragment-Based Methods in Drug Discovery

📁 Fragment-Based Methods in Drug Discovery

✍ Anthony E. Klon (eds.) 📂 Library 📅 2015 🏛 Humana Press 🌐 English

Fragment-Based Drug Discovery: A Practic

📁 Fragment-Based Drug Discovery: A Practical Approach

✍ Edward Zartler, Michael Shapiro 📂 Library 📅 2008 🏛 Wiley 🌐 English

Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules - fragments of larger molecules. It is a faster, cheaper, smarter way to do drug discovery, as shown by the number of pharmaceutical companies that have embraced this approach and the biotechn

Fragment-based Drug Discovery: Lessons a

📁 Fragment-based Drug Discovery: Lessons and Outlook

✍ Daniel A. Erlanson, Wolfgang Jahnke (eds.) 📂 Library 📅 2016 🏛 Wiley-VCH 🌐 English

<p>From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often yielding results where other methods have failed. Written by the pioneers in the field, this book provides a comprehensive overview of current meth