Fragment Based Drug Design: Tools, Practical Approaches, and Examples

Fragment-Based Drug Discovery: A Practic

📁 Fragment-Based Drug Discovery: A Practical Approach

✍ Edward Zartler, Michael Shapiro 📂 Library 📅 2008 🏛 Wiley 🌐 English

Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules - fragments of larger molecules. It is a faster, cheaper, smarter way to do drug discovery, as shown by the number of pharmaceutical companies that have embraced this approach and the biotechn

Library Design, Search Methods, and Appl

📁 Library Design, Search Methods, and Applications of Fragment-Based Drug Design

✍ Rachelle J. Bienstock (Eds.) 📂 Library 📅 2011 🏛 American Chemical Society 🌐 English

Content: Overview : fragment based drug design -- Designing and searching fragment libraries -- Validation of reaction vectors for de novo design -- Design and application of fragment libraries for protein crystallography -- Ligand-based virtual screening using Bayesian infe

Drug Design: Structure- and Ligand-Based

📁 Drug Design: Structure- and Ligand-Based Approaches

✍ Kenneth M. Merz (editor), Dagmar Ringe (editor), Charles H. Reynolds (editor) 📂 Library 📅 2010 🏛 Cambridge University Press 🌐 English

Structure-based (SBDD) and ligand-based (LBDD) drug design are extremely important and active areas of research in both the academic and commercial realms. This book provides a complete snapshot of the field of computer-aided drug design and associated experimental approaches. Topics covered include

Drug Design: Structure- and Ligand-Based

📁 Drug Design: Structure- and Ligand-Based Approaches

✍ Kenneth M. Merz, Dagmar Ringe, Charles H. Reynolds 📂 Library 📅 2010 🏛 Cambridge University Press 🌐 English

Structure-based (SBDD) and ligand-based (LBDD) drug design are extremely important and active areas of research in both the academic and commercial realms. This book provides a complete snapshot of the field of computer-aided drug design and associated experimental approaches. Topics covered include

Structure-Based Drug Design: Experimenta

📁 Structure-Based Drug Design: Experimental and Computational Approaches

✍ W. L. Duax, J. F. Griffin (auth.), Penelope W. Codding (eds.) 📂 Library 📅 1998 🏛 Springer Netherlands 🌐 English

Structure-Based Drug Design brings together scientists working on different aspects of the subject, demonstrating the necessary collaboration and interdisciplinary approach to this complex area. The focus is on X-ray crystallographic and computational approaches. The general aspects of t

Fragment-based Approaches in Drug Discov

📁 Fragment-based Approaches in Drug Discovery (Methods and Principles in Medicinal Chemistry)

✍ Wolfgang Jahnke, Daniel A. Erlanson (Editors), Raimund Mannhold, Hugo Kubinyi, G 📂 Library 📅 2006 🏛 Wiley-VCH 🌐 English

This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers i